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Obstetrics Expert Joins MSU

Sascha Drewlo

Sascha Drewlo recently joined MSU as associate professor in the Department of Obstetrics, Gynecology and Reproductive Biology in the College of Human Medicine.

His research focuses on the early detection of fetal and placental disorders. Along with deciphering the underlying molecular mechanisms of abnormal placentation, he is working to ultimately develop novel intervention strategies for preeclampsia, as well as preterm birth and intrauterine growth restriction.

He is also investigating the potential of cervical trophoblast for novel non-invasive fetal diagnosis (Science Translational Medicine, 2016). His research, and research in collaboration with Dr. Armant at Advanced Reproductive Testing, LLC, develops novel approaches for fetal genetic analysis and overall pregnancy status during the first trimester of pregnancy from a simple pap smear. This has the potential to change the way to assess pregnancies, as it can be safely performed at as early as five weeks.

Drewlo received his master’s degree in 2000 from the University of Münster in Germany and his doctoral degree from German Sport University, Cologne, Germany, in 2006. Following his postdoctoral training at the Lulenfeld Tanenbaum Research Institute, University of Toronto, Canada, he was appointed assistant professor in the Department of Obstetrics, Gynecology and Reproductive Biology at Wayne State University.

He has since been awarded the Basil O’Connor Stater Scholar Research Award from the March of Dimes (2014-16). He also received the Gabor Than Award in 2016 from the International Federation of Placenta Associations (IFPA), which acknowledges outstanding contributions to the field of placentology to an early career investigator.

Research Interests:

  • Human trophoblast cell differentiation
  • Biotechnology
  • Placental Biology
  • Automated Assay Development
  • Early Human Development
  • Fetal Complications

Recent Publications: 
Glial cell missing-1 transcription factor is required for the differentiation of the human trophoblast.Baczyk D, Drewlo S, Proctor L, Dunk C, Lye S, Kingdom J.Cell death and differentiation. 2009; 16(5):719-27.PubMed [journal]PMID: 19219068
Re: Becker C, Heidersdorf S, Drewlo S, et al. Efficacy of epidural perineural injections with autologous conditioned serum for lumbar radicular compression. Spine 2007;32:1803-8.Birkenmaier C, Leu HF, Veihelmann A.Spine. 2008; 33(5):576.PubMed [journal]PMID: 18317206
Fusion assays and models for the trophoblast.Drewlo S, Baczyk D, Dunk C, Kingdom J.Methods in molecular biology (Clifton, N.J.). 2008; 475:363-82.PubMed [journal]PMID: 18979255

For a complete list of papers and publications, click here.

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